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Article

Targeting the AKT Pathway in Glioblastoma

1 Aug 2011

Abstract excerpt

Glioblastoma multiforme (GBM) is the most common malignant brain tumor in adults. The treatment options for patients diagnosed with GBM are limited and the current median survival is 14-16 months following diagnosis. Genetic mutations have been identified that act as drivers of GBM growth and these should be considered as a basis for identifying novel therapeutic strategies. AKT is a downstream serine/threonine...

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PMID: 21827416
DOI: 10.2174/138161211797249224

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