Article

Trimethylamine, a gut bacteria metabolite and air pollutant, increases blood pressure and markers of kidney damage including proteinuria and KIM-1 in rats.

2022-08-25

Abstract excerpt

<title>Abstract</title> <p>Background trimethylamine oxide (TMAO) is a biomarker in cardiovascular and renal diseases. TMAO originates from the oxidation of trimethylamine (TMA), a product of gut microbiota and manufacturing industries-derived pollutant, by flavin monooxygenases (FMOs). The effect of chronic exposure to TMA on cardiovascular and renal systems is undetermined. Methods metabolic, hemodynamic, ech...

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Literature Corpus work: 38564a23-6bab-50d1-b34c-19288b18f979
DOI: 10.21203/rs.3.rs-1944800/v1

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