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Brain and Lung Cross-Protection against Ancestral or Emerging SARS-CoV-2 by Intranasal Lentiviral Vaccination in a New hACE2 Transgenic Murine Model

2021-04-12

Abstract excerpt

<title>Abstract</title> <p>COVID-19 vaccines already in use or in clinical development may have safety concerns, limited immunogenicity in high-risk groups or reduced efficacy against emerging SARS-CoV-2 variants. In addition, although the neurotropism of SARS-CoV-2 is well established, the vaccine strategies currently developed have not taken into account the protection of the central nervous system. Here, we ge...

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Literature Corpus work: 3849d2af-6685-532a-9930-f8348e56ffc2
DOI: 10.21203/rs.3.rs-415309/v1

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