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Article

Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humans

2 Sept 2022

Abstract excerpt

Individuals who receive a third mRNA vaccine dose show enhanced protection against severe COVID-19, but little is known about the impact of breakthrough infections on memory responses. Here, we examine the memory antibodies that develop after a third or fourth antigenic exposure by Delta or Omicron BA.1 infection, respectively. A third exposure to antigen by Delta breakthrough increases the number of memory B...

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PMID: 36149398
DOI: 10.1084/jem.20221006

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