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Article

An RNAi-based suppressor screen identifies interactors of the Myt1 ortholog of Caenorhabditis elegans.

G3 (Bethesda, Md.) - 8 Oct 2014

Allen Anna K, Nesmith Jessica E, Golden Andy

Abstract excerpt

Oocyte maturation in all species is controlled by a protein complex termed the maturation promoting factor (MPF). MPF comprises a cyclin-dependent kinase (CDK) and its partner cyclin, and it is regulated by dueling regulatory phosphorylation events on the CDK. In Caenorhabditis elegans, the Wee1/Myt1 ortholog WEE-1.3 provides the inhibitory phosphorylations on CDK-1 that keep MPF inactive and halt meiosis. Prior...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25298536
DOI: 10.1534/g3.114.013649
PMCID: PMC4267929

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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