Article

A survey of human cancer-germline genes: linking X chromosome localization, DNA methylation and sex-biased expression in early embryos

2025-05-23

Abstract excerpt

Human cancer-germline (CG) genes are a group of testis-specific genes that become aberrantly activated in various tumors. Ongoing studies aim to understand their functions in order to evaluate their potential as anti-cancer therapeutic targets. Evidence suggests the existence of subcategories of CG genes, depending on location on autosomal or sex chromosomes, reliance on DNA methylation for transcriptional regulat...

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Literature Corpus work: 382b4afb-0da6-59b0-9805-a87a4ece4fff
DOI: 10.1101/2025.05.19.654804

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