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Article

Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/ß-catenin, and mTOR signaling during corticogenesis

2020-10-07

Abstract excerpt

<title>Abstract</title> <p>Corticogenesis is one of the most critical and complicated processes during embryonic brain development. Any slight impairment in corticogenesis could cause neurodevelopmental disorders such as Fragile X syndrome (FXS), of which symptoms contain intellectual disability (ID) and autism spectrum disorder (ASD). Fragile X mental retardation protein (FMRP), an RNA-binding protein responsibl...

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Literature Corpus work
37f6f894-f31a-50cb-a1d1-29793ed806fa
DOI
10.21203/rs.3.rs-86009/v1
Open publication

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Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/ß-catenin, and mTOR signaling during corticogenesisDOI 10.21203/rs.3.rs-86009/v1
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