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Article

Fragile X-related protein family: a double-edged sword in neurodevelopmental disorders and cancer.

Critical reviews in biochemistry and molecular biology - 1 Oct 2020

Majumder Mrinmoyee, Johnson Roger H, Palanisamy Viswanathan

Abstract excerpt

The fragile X-related (FXR) family proteins FMRP, FXR1, and FXR2 are RNA binding proteins that play a critical role in RNA metabolism, neuronal plasticity, and muscle development. These proteins share significant homology in their protein domains, which are functionally and structurally similar to each other. FXR family members are known to play an essential role in causing fragile X mental retardation syndrome...

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Identifiers

PMID: 32878499
DOI: 10.1080/10409238.2020.1810621
PMCID: PMC7695039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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