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Article

Concise review: Fragile X proteins in stem cell maintenance and differentiation.

Stem cells (Dayton, Ohio) - 1 Jul 2014

Li Yue, Zhao Xinyu

Abstract excerpt

Fragile X syndrome (FXS), the most common genetic form of autism spectrum disorder, is caused by deficiency of the fragile X mental retardation protein (FMRP). Despite extensive research and scientific progress, understanding how FMRP regulates brain development and function remains a major challenge. FMRP is a neuronal RNA-binding protein that binds about a third of messenger RNAs in the brain and controls their...

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Identifiers

PMID: 24648324
DOI: 10.1002/stem.1698
PMCID: PMC4255947

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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