Back to search

Article

Genetic Modulation of Protein Expression in Rat Brain

2024-02-21

Abstract excerpt

Genetic variations in protein expression are implicated in a broad spectrum of common diseases and complex traits. However, the fundamental genetic architecture and variation of protein expression have received comparatively less attention than either mRNA or classical phenotypes. In this study, we systematically quantified proteins in the brains of a large family of rats using tandem mass tag (TMT)-based quantita...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3775293c-768e-56f5-8903-0676c6521b9c
DOI
10.1101/2024.02.17.580840
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Genetic Modulation of Protein Expression in Rat BrainDOI 10.1101/2024.02.17.580840
Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disorders.Semantic proximity
Genetic regulation of human brain proteome reveals proteins implicated in psychiatric disordersSemantic proximity
Unraveling Neuro-Proteogenomic Landscape and Therapeutic Implications for Human Behaviors and Psychiatric DisordersSemantic proximity
Identification of Genetic Variants Regulating the Abundance of Clinically Relevant Plasma Proteins using the Diversity Outbred Mouse ModelSemantic proximity
Genetic analysis of the mouse brain proteome.Semantic proximity
Genetic control of the human brain proteomeSemantic proximity
Sex differences in brain protein expression and disease.Semantic proximity
Proteomic studies related to genetic determinants of variability in protein concentrations.Semantic proximity
Similar and different: systematic investigation of proteogenomic variation between sexes and its relevance for human diseasesSemantic proximity
Defining the consequences of genetic variation on a proteome-wide scale.Semantic proximity
Human Brain Proteome-wide Association Study Provides Insights into the Genetic Components of Protein Abundance in ObesitySemantic proximity
Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.Semantic proximity
Select a neighboring publication to make it the new centre.