Article

The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculation

2024-02-22

Abstract excerpt

Rift Valley fever (RVF) is an important zoonotic viral disease affecting several species of domestic and wild ruminants, causing major economic losses and dozens of human deaths in various geographical areas of Africa, where it is endemic. Although it is not present in Europe, there is a risk of its introduction and spread linked to globalisation and climate change. At present, the only measure that could help to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 37576008-4a96-5f49-ab3b-6938d879060b
DOI: 10.1101/2024.02.20.581149

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Rift Valley fever (RVF) vaccine candidate 40Fp8 shows an extreme attenuation in IFNARKO mice following intranasal inoculationDOI 10.1101/2024.02.20.581149Read

Evaluations of rationally designed rift valley fever vaccine candidate RVax-1 in mosquito and rodent modelsSemantic proximity Read

Rift Valley Fever Virus MP-12 Vaccine Is Fully Attenuated by a Combination of Partial Attenuations in the S, M, and L SegmentsSemantic proximity Read

Characterisation of immune responses and protective efficacy in mice after immunisation with Rift Valley Fever virus cDNA constructsSemantic proximity Read

Rapid accumulation of virulent rift valley Fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the m RNA.Semantic proximity Read

Attenuation and protective efficacy of Rift Valley fever phlebovirus rMP12-GM50 strain.Semantic proximity Read

Single-Dose Immunization with Virus Replicon Particles Confers Rapid Robust Protection against Rift Valley Fever Virus ChallengeSemantic proximity Read

The dominant-negative inhibition of double-stranded RNA-dependent protein kinase PKR increases the efficacy of Rift Valley fever virus MP-12 vaccine.Semantic proximity Read

Perspectives of Next-Generation Live-Attenuated Rift Valley Fever Vaccines for Animal and Human UseSemantic proximity Read

Comparative study of two Rift Valley fever virus field strains circulating in Mauritania in 2010 and 2013 reveals the high virulence of the MRU25010-30 strain isolated from camelSemantic proximity Read

Rift Valley fever virus: Unanswered questions.Semantic proximity Read

Safety and Efficacy Upon Infection in Sheep with Rift Valley Fever Virus ZH548-rA2, a Triple Mutant Rescued VirusSemantic proximity Read

Novel replication-competent reporter-expressing Rift Valley Fever Viruses for molecular studiesSemantic proximity Read