Article
Rapid accumulation of virulent rift valley Fever virus in mice from an attenuated virus carrying a single nucleotide substitution in the m RNA.
PloS one - 1 Apr 2010
Morrill John C, Ikegami Tetsuro, Yoshikawa-Iwata Naoko, Lokugamage Nandadeva, Won Sungyong, Terasaki Kaori, Zamoto-Niikura Aya, Peters C J, Makino Shinji
Abstract excerpt
BACKGROUND: Rift Valley fever virus (RVFV), a member of the genus Phlebovirus within the family Bunyaviridae, is a negative-stranded RNA virus with a tripartite genome. RVFV is transmitted by mosquitoes and causes fever and severe hemorrhagic illness among humans, while in livestock it causes fever and high abortion rates. METHODOLOGY/PRINCIPAL FINDINGS: Sequence analysis showed that a wild-type RVFV ZH501...
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