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Evaluations of rationally designed rift valley fever vaccine candidate RVax-1 in mosquito and rodent models

21 Sept 2022

Abstract excerpt

Rift Valley fever (RVF) is a mosquito-borne zoonosis endemic to Africa and the Arabian Peninsula, which causes large outbreaks among humans and ruminants. Single dose vaccinations using live-attenuated RVF virus (RVFV) support effective prevention of viral spread in endemic countries. Due to the segmented nature of RVFV genomic RNA, segments of vaccine strain-derived genomic RNA could be incorporated into...

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PMID: 36131104
DOI: 10.1038/s41541-022-00536-3

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