Article
Attenuation and protective efficacy of Rift Valley fever phlebovirus rMP12-GM50 strain.
Vaccine - 4 Dec 2017
Ly Hoai J, Nishiyama Shoko, Lokugamage Nandadeva, Smith Jennifer K, Zhang Lihong, Perez David, Juelich Terry L, Freiberg Alexander N, Ikegami Tetsuro
Abstract excerpt
Rift Valley fever (RVF) is a mosquito-borne zoonotic disease endemic to Africa and the Arabian Peninsula that affects sheep, cattle, goats, camels, and humans. Effective vaccination of susceptible ruminants is important for the prevention of RVF outbreaks. Live-attenuated RVF vaccines are in general highly immunogenic in ruminants, whereas residual virulence might be a concern for vulnerable populations. It is...
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