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Genetic and Epigenetic Regulation of Inflammatory Genes Drives Calcific Aortic Valve Disease (CAVD)

2025-05-16

Abstract excerpt

<h4>Introduction</h4> Calcific aortic valve disease (CAVD) is the most common valvular disorder in older adults, characterized by progressive fibrosis, calcification, and impaired blood flow. Despite its growing burden, no effective pharmacological treatments exist. Inflammation and epigenetic dysregulation are increasingly recognized as central to CAVD pathogenesis. This study aimed to identify key inflammatory g...

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Literature Corpus work
37522e67-3e2e-5ac4-bde2-02b44b683960
DOI
10.1101/2025.05.15.25327710
Open publication

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