Article

Adult B-Cell Acute Lymphoblastic Leukaemia Antigens and Enriched Pathways Identify New Targets for Therapy

2025-02-17

Abstract excerpt

<h4>Background: </h4> Adult B-cell acute lymphoblastic leukaemia (aB-ALL) is characterised by abnormal differentiation and proliferation of lymphoid progenitors. Despite a significant improvement in relapse-free and overall survival for children with B-ALL, aB-ALL has a particularly poor prognosis with a 5-year survival rate of 20%. First remission is achieved for most patients but relapse is common with a high as...

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Literature Corpus work: 37432bbf-cd06-57c8-8009-43ac66a52dec
DOI: 10.20944/preprints202502.1306.v1

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