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Article

High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia

12 Jan 2010

Abstract excerpt

Overexpression of BAALC is an adverse prognostic factor in adults with cytogenetically normal acute myeloid leukemia and T-cell acute lymphoblastic leukemia (ALL). Here, we analyzed the prognostic significance of BAALC in B-precursor ALL. BAALC MRNA expression was determined in 368 primary adult B-precursor ALL patients enrolled on the 06/99 and 07/03 GMALL trials. Patients were grouped into tertiles according to...

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PMID: 20065290
DOI: 10.1182/blood-2009-09-241943

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