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Multi-Cohort Transcriptomic Subtyping of B-Cell Acute Lymphoblastic Leukemia

20 Apr 2022

Abstract excerpt

RNA sequencing provides a snapshot of the functional consequences of genomic lesions that drive acute lymphoblastic leukemia (ALL). The aims of this study were to elucidate diagnostic associations (via machine learning) between mRNA-seq profiles, independently verify ALL lesions and develop easy-to-interpret transcriptome-wide biomarkers for ALL subtyping in the clinical setting. A training dataset of 1279 ALL...

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PMID: 35562965
DOI: 10.3390/ijms23094574

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