Article

A Natural Depsipeptide Antibiotic that Targets the E site of the Bacterial Ribosome

2025-07-03

Abstract excerpt

<title>Abstract</title> <p>A significant challenge in addressing the antibiotic resistance crisis is identifying new antimicrobial compounds. Although natural products produced by fungi and bacteria, particularly actinomycetes, have been the source of most antibiotics discovered over the past 80 years, they have fallen out of favor due to the frequent rediscovery of known drug scaffolds. The current perception is...

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Literature Corpus work: ffcfee9a-6d4c-539e-8d5b-9ea5d0cc1ed2
DOI: 10.21203/rs.3.rs-6925047/v1

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