Article

MAP2 is Differentially Phosphorylated in Schizophrenia, Altering its Function

2019-06-27

Abstract excerpt

Schizophrenia (Sz) is a highly polygenic disorder, with common, rare, and structural variants each contributing only a small fraction of overall disease risk. Thus, there is a need to identify downstream points of convergence that can be targeted with therapeutics. Reduction of Microtubule-associated Protein 2 (MAP2) immunoreactivity (MAP2-IR) is present in individuals with Sz, despite no change in MAP2 protein le...

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Literature Corpus work: 3701eb8d-e88d-51d1-9325-e59169f87758
DOI: 10.1101/683912

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