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Article

Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with  different metabolic pathways in murine livers

2020-11-30

Abstract excerpt

Over the last decade oxylipins have become more recognized for their involvement in several diseases. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen are known to inhibit cyclooxygenase (COX) enzymes, but how NSAIDs affect oxylipins, in addition to COX products, in animal tissues is not well understood. Investigation of oxylipins in livers from male and female mice treated with 100mg/kg/day of ibu...

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Identifiers and source

Literature Corpus work
36fe01a3-738b-574a-823d-4a6ed3b048be
DOI
10.21203/rs.3.rs-109297/v1
Open publication

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Ibuprofen alters epoxide hydrolase activity and epoxy-oxylipin metabolites associated with different metabolic pathways in murine liversDOI 10.21203/rs.3.rs-109297/v1
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