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Targeting squalene epoxidase in the treatment of metabolic-related diseases: current research and future directions

22 Nov 2024

Abstract excerpt

Metabolic-related diseases are chronic diseases caused by multiple factors, such as genetics and the environment. These diseases are difficult to cure and seriously affect human health. Squalene epoxidase (SQLE), the second rate-limiting enzyme in cholesterol synthesis, plays an important role in cholesterol synthesis and alters the gut microbiota and tumor immunity. Research has shown that SQLE is expressed in...

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PMID: 39588004
DOI: 10.7717/peerj.18522

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