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Human iPSC Derived Enamel Organoid Guided by Single-Cell Atlas of Human Tooth Development

2022-08-10

Abstract excerpt

Tooth enamel secreted by ameloblasts is the hardest material in the human body, acting as a shield protecting the teeth. However, the enamel is gradually damaged or partially lost in over 90% of adults and cannot be regenerated due to a lack of ameloblasts in erupted teeth. Here we use sci-RNA-seq to establish a spatiotemporal single-cell atlas for the developing human tooth and identify regulatory mechanisms cont...

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Literature Corpus work
bf53f4ce-c473-5fb4-9b8c-fdc12e0894f7
DOI
10.1101/2022.08.09.503399
Open publication

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Human iPSC Derived Enamel Organoid Guided by Single-Cell Atlas of Human Tooth DevelopmentDOI 10.1101/2022.08.09.503399
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