Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Loss of epithelial FAM20A in mice causes amelogenesis imperfecta, tooth eruption delay and gingival overgrowth

1 Jun 2016

Abstract excerpt

FAM20A has been studied to a very limited extent. Mutations in human FAM20A cause amelogenesis imperfecta, gingival fibromatosis and kidney problems. It would be desirable to systemically analyse the expression of FAM20A in dental tissues and to assess the pathological changes when this molecule is specifically nullified in individual tissues. Recently, we generated mice with a Fam20A-floxed allele containing the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone and Dental Protein Studies
Share to dental development and anomalies
Share to Oral and Maxillofacial Pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27281036
DOI: 10.1038/ijos.2016.14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Loss of epithelial FAM20A in mice causes amelogenesis imperfecta, tooth eruption delay and gingival overgrowthPMID 27281036Read ↗

FAM20A is essential for amelogenesis, but is dispensable for dentinogenesis.Semantic proximity Read ↗

Ablation of Fam20c causes amelogenesis imperfecta via inhibiting Smad dependent BMP signaling pathwaySemantic proximity Read ↗

Amelogenesis imperfecta and other biomineralization defects in Fam20a and Fam20c null mice.Semantic proximity Read ↗

FAM20A mutations associated with enamel renal syndrome.Semantic proximity Read ↗

Human and mouse enamel phenotypes resulting from mutation or altered expression of AMEL, ENAM, MMP20 and KLK4.Semantic proximity Read ↗

FAM20A mutations can cause enamel-renal syndrome (ERS).Semantic proximity Read ↗

Generation and characterization of a murine amelogenesis imperfecta model.Semantic proximity Read ↗

FAM20A mutations and transcriptome analyses of dental pulp tissues of enamel renal syndrome.Semantic proximity Read ↗

FAM20A deficiency impairs osteogenesis in enamel–renal syndromeSemantic proximity Read ↗

Whole-Exome sequencing identifies FAM20A mutations as a cause of amelogenesis imperfecta and gingival hyperplasia syndrome.Semantic proximity Read ↗

A Suite of Mouse Reagents for Studying AmelogenesisSemantic proximity Read ↗

In-depth investigation of FAM20A insufficiency effects on deciduous dental pulp cells: Altered behaviours, osteogenic differentiation, and inflammatory gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.