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Article

A mouse model expressing a truncated form of ameloblastin exhibits dental and junctional epithelium defects.

Matrix biology : journal of the International Society for Matrix Biology - 1 Jun 2009

Wazen Rima M, Moffatt Pierre, Zalzal Sylvia Francis, Yamada Yoshihiko, Nanci Antonio

Abstract excerpt

Ameloblastin (AMBN) is the second most abundant extracellular matrix protein produced by the epithelial cells called ameloblasts and is found mainly in forming dental enamel. Inactivation of its expression by gene knockout results in absence of the enamel layer and its replacement by a thin layer of dysplastic mineralized matrix. The objective of this study was to further characterize the enamel organ and...

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Source

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Identifiers

PMID: 19375505
DOI: 10.1016/j.matbio.2009.04.004
PMCID: PMC2727877

Genes

AMBN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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