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Article

Longitudinal Epigenome-Wide Methylation Study of Cognitive Decline and Motor Progression in Parkinson’s Disease

5 Apr 2019

Abstract excerpt

BACKGROUND: DNA methylation studies in Parkinson's disease (PD) thus far have focused on disease susceptibility but not progression. OBJECTIVE: In this epigenome-wide association study (EWAS), we aim to identify methylation markers associated with faster cognitive decline or motor progression in PD. METHODS: We included 232 PD patients from the Parkinson's Environment and Gene follow-up study who provided blood...

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PMID: 30958317
DOI: 10.3233/jpd-181549

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