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Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins

12 Dec 2017

Abstract excerpt

As the world’s population ages, the age-related cognitive decline presents a great challenge to world’s healthcare systems. One of the molecular mechanisms implicated in cognitive ageing is DNA methylation, an epigenetic modification known to be a key player in memory formation, maintenance, and synaptic plasticity. Using the twin design we performed an epigenome-wide association study in a population of 486...

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PMID: 29311901
DOI: 10.3389/fnagi.2017.00413

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