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Targeted induction of <i>de novo</i> Fatty acid synthesis enhances MDV replication in a COX-2/PGE <sub>2α</sub> dependent mechanism through EP2 and EP4 receptors engagement

2018-05-16

Abstract excerpt

Many viruses alter de novo Fatty Acid (FA) synthesis pathway, which can increase availability of energy for replication and provide specific cellular substrates for particle assembly. Marek’s disease virus (MDV) is a herpesvirus that causes deadly lymphoma and has been linked to alterations of lipid metabolism in MDV-infected chickens. However, the role of lipid metabolism in MDV replication is largely unknown. W...

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Literature Corpus work
35e678ad-c83c-5118-b841-ab9c043514e8
DOI
10.1101/323840
Open publication

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