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Article

Cyclooxygenase‐2 facilitates dengue virus replication and serves as a potential target for developing antiviral agents

20 Mar 2017

Abstract excerpt

Abstract Cyclooxygenase-2 (COX-2) is one of the important mediators of inflammation in response to viral infection, and it contributes to viral replication, for example, cytomegalovirus or hepatitis C virus replication. The role of COX-2 in dengue virus (DENV) replication remains unclear. In the present study, we observed an increased level of COX-2 in patients with dengue fever compared with healthy donors....

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PMID: 28317866
DOI: 10.1038/srep44701

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