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Article

The Oxysterol 25-Hydroxycholesterol Inhibits Replication of Murine Norovirus

24 Jan 2019

Abstract excerpt

Cholesterol, an essential component of mammalian cells, is also an important factor in the replicative-cycles of several human and animal viruses. The oxysterol, 25-hydroxycholesterol, is produced from cholesterol by the enzyme, cholesterol 25-hydroxylase. 25-hydroxycholesterol (25-HC) has been shown to have anti-viral activities against a wide range of viruses, including a range of positive-sense RNA viruses. In...

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PMID: 30682775
DOI: 10.3390/v11020097

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