Article

Ultra-low coverage genome-wide association study – insights into gestational age using 17,844 embryo samples with preimplantation genetic testing

2022-06-16

Abstract excerpt

<h4>Background</h4> Very low coverage (0.1 to 1x) whole genome sequencing (WGS) has become a promising and affordable approach to discover genomic variants of human populations for Genome-Wide Association Study (GWAS). To support genetic screening using Preimplantation Genetic Testing (PGT) in a large population, the sequencing coverage goes below 0.1x to an ultra-low level. However, its feasibility and effectiven...

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Literature Corpus work: 35c9d434-b631-5c2a-a9fd-f82109cea8bc
DOI: 10.1101/2022.06.15.22276464

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