Article

An Effective Gene-Based Rare Variant Association Analysis Pipeline for Case-Control Studies of Disease

2020-12-02

Abstract excerpt

<title>Abstract</title> <p>BackgroundIn complex disease studies, genome-wide association study (GWAS) has been successfully used for identifying associated genetic risk loci. In fact, only a small fraction of the apparent heritability can be explained by common variants. Because research efforts have largely focused on common genetic variants, the missing heritability could be mostly due to rare genetic variants....

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Literature Corpus work: efd25baf-4dd8-5850-aec9-439055c734bd
DOI: 10.21203/rs.3.rs-116709/v1

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