Article

From Pathway to Patient: Molecular Dysregulation as Basis for Minimal Sequential Intervention Strategy in Basal-Like Breast Cancer

2026-03-05

Abstract excerpt

<title>Abstract</title> <p>Aggressive breast cancer subtypes like triple-negative and basal-like tumors exhibit widespread dysregulation across multiple signaling pathways, requiring multi-pathway therapeutic strategies. Boolean network models can integrate large-scale genomic data with mechanistic pathway knowledge, but face scalability challenges. We present BBCN118, a modular Boolean network framework comprisi...

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Literature Corpus work: 3598ccdc-968a-5397-b216-505683e38113
DOI: 10.21203/rs.3.rs-8942485/v1

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