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Dorsal Striatum Transcriptome Profile Profound Shift in Repeated Aggression Mouse Model Converged to Networks of 12 Transcription Factors after Fighting Deprivation.

Genes - 22 Dec 2021

Babenko Vladimir, Redina Olga, Smagin Dmitry, Kovalenko Irina, Galyamina Anna, Babenko Roman, Kudryavtseva Natalia

Abstract excerpt

Both aggressive and aggression-deprived (AD) species represent pathologic cases intensely addressed in psychiatry and substance abuse disciplines. Previously, we reported that AD mice displayed a higher aggressive behavior score than the aggressive group, implying the manifestation of a withdrawal effect. We employed an animal model of chronic social conflicts, curated in our lab for more than 30 years. In the...

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Identifiers

PMID: 35052361
DOI: 10.3390/genes13010021
PMCID: PMC8774333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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