Article

Maternal thyroid hormone increases neural cell diversity during zebrafish spinal cord neurodevelopment

2022-02-27

Abstract excerpt

Maternally derived thyroid hormone (MT3) is a fundamental factor for vertebrate neurodevelopment. In humans, mutations on the T3 exclusive transporter monocarboxylic acid transporter 8 (MCT8) lead to the Allan-Herndon-Dudley syndrome (AHDS). Patients with AHDS present severe underdevelopment of the central nervous system with cognitive and locomotory consequences. Functional impairment of the zebrafish T3 exclusiv...

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Literature Corpus work: 3545d32f-1bd8-5637-9c64-289ebefd449d
DOI: 10.1101/2022.02.26.482108

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