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Article

GLUT3 gene expression is critical for embryonic growth, brain development and survival.

Molecular genetics and metabolism - 1 Apr 2014

Carayannopoulos Mary O, Xiong Fuxia, Jensen Penny, Rios-Galdamez Yesenia, Huang Haigen, Lin Shuo, Devaskar Sherin U

Abstract excerpt

Glucose is the primary energy source for eukaryotic cells and the predominant substrate for the brain. GLUT3 is essential for trans-placental glucose transport and highly expressed in the mammalian brain. To further elucidate the role of GLUT3 in embryonic development, we utilized the vertebrate whole animal model system of Danio rerio as a tractable system for defining the cellular and molecular mechanisms...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24529979
DOI: 10.1016/j.ymgme.2014.01.013
PMCID: PMC4536922

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