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Investigation of the Role of the LC3 Conjugation System in Autophagy for Human Reward System Reactivity

2025-03-29

Abstract excerpt

<h4>Objectives</h4> The dopaminergic reward system is involved in the etiology of psychiatric disorders, and autophagy has been suggested to interfere with dopamine release. LC3 conjugation plays a key role in autophagy and comprises modification of autophagy protein LC3 with phosphatidylethanolamine. We investigated whether LC3 conjugation may impact on the strength of activation in key regions of the mesolimbic...

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Literature Corpus work
3513f9bc-ba56-5f64-b341-25b2420e5696
DOI
10.1101/2025.03.26.645396
Open publication

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Investigation of the Role of the LC3 Conjugation System in Autophagy for Human Reward System ReactivityDOI 10.1101/2025.03.26.645396
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