Article

TMEM87A/EBP/7-DHC/7-DHD Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion

2026-07-10

Abstract excerpt

<title>Abstract</title> <p> Understanding the mechanisms by which Kirsten rat sarcoma (KRAS) mutations drive the development and progression of pancreatic ductal adenocarcinoma (PDAC) may promote the discovery of novel therapeutic strategies for KRAS‑mutant PDAC (KRAS <sup>mut</sup> ‑PDAC). Here, our study confirms that transmembrane protein 87A (TMEM87A), upregulated by KRAS via transcription 3 (STAT3), is ab...

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Literature Corpus work: 350cbe65-cec0-55e1-81d7-fce1d9138269
DOI: 10.21203/rs.3.rs-10197859/v1

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