Article
Ferroptosis: New Strategies and Ideas for the Treatment of Pancreatic Ductal Adenocarcinoma.
Frontiers in bioscience (Landmark edition) - 23 Jan 2024
Yang Chengru, Dong Qingfu, Bao Haolin, Ge Yifei, Xu Zhaoqiang, Li Jinglin, Jiang Xingming, Xu Yi, Zhong Xiangyu
Abstract excerpt
Pancreatic cancer is a malignancy that affects the digestive tract and has a low 5-year survival rate of lower than 15%. Owing to its genetic mutation and metabolic complexity, pancreatic cancer is difficult to treat with surgical resection, radiotherapy, and chemotherapy. The predominant modality of pancreatic cancer is pancreatic ductal adenocarcinoma (PDAC), primarily attributed to mutations in KRAS gene....
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