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Automated Intelligent Microscopy for Phenotype Identification, Spatial Localization, and Retargeting of Cells.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Pelicci Simone, Furia Laura, Spadari Francesco, Grigolato Roberto, Calabrese Luca, Girolami Ilaria, Faretta Mario

Abstract excerpt

Heterogeneity is a hallmark of cancer progression, characterized by genetic, transcriptional, and protein expression variability, as well as dynamic interactions within the tumor microenvironment. Primary tumors often harbor multiple, spatially distinct cellular subpopulations, complicating efforts to achieve comprehensive molecular characterization. Recent progress in molecular diagnostics and sequencing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 41629720
DOI: 10.1007/978-1-0716-5154-4_15

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