Article

Development of Synthetic Modulator Enabling Long-Term Propagation and Neurogenesis of Human-Derived Neural Progenitor Cells

2023-05-15

Abstract excerpt

Neural progenitor cells (NPCs) are important cells for in vitro drug screening and the cell-based therapy for brain-related disorders, which requires well-defined and reproducible culture systems. Current strategy the use of protein growth factors presents challenges in terms of reproducibility and cost. In this study, we have developed a novel DNA-based modulator to regulate FGFR signaling of NPCs, enabling maint...

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Literature Corpus work: 34e11f83-9f13-5095-adae-bcbd10736c22
DOI: 10.1101/2023.05.15.540695

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