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Control of Stemness by Fibroblast Growth Factor Signaling in Stem Cells and Cancer Stem Cells

1 Jan 2009

Abstract excerpt

Since the discovery of stem cells, scientists have invested tremendous effort in establishing in vitro culture conditions in order to maintain the self-renewal and efficient proliferative capabilities of stem cells by manipulating a variety of growth factors. Fibroblast growth factor (FGF) is one of the most common growth factors used to expand stem cells, including human embryonic stem (hES) cells and several...

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PMID: 19149625
DOI: 10.2174/157488809787169048

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