Article

Viral-Induced Alternative Splicing of Host Genes Promotes Influenza Replication

2020-05-30

Abstract excerpt

Viral infection induces the expression of numerous host genes that impact the outcome of infection. Here we show that infection of human lung epithelial cells with Influenza A virus (IAV) also induces a broad program of alternative splicing of host genes. While these splicing-regulated genes are not enriched for canonical regulators of viral infection, we find that many of these genes do impact replication of IAV....

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Identifiers and source

Literature Corpus work: 34c0d142-78e4-53e3-9235-bda04d1b53e5
DOI: 10.1101/2020.05.28.122044

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