Article

Defective influenza A virus RNA products mediate MAVS-dependent upregulation of human leukocyte antigen class I proteins

2020-01-31

Abstract excerpt

<h4>ABSTRACT</h4> Influenza A virus (IAV) increases presentation of class I human leukocyte antigen (HLA) proteins that limit antiviral responses mediated by natural killer (NK) cells, but molecular mechanisms have not yet been fully elucidated. We observed that infection with A/Fort Monmouth/1/1947 (H1N1) IAV significantly increased presentation of HLA-B, -C and -E on lung epithelial cells. Virus entry was not s...

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Literature Corpus work: 108d5a0b-6fd2-546d-8c4f-b433701cbf19
DOI: 10.1101/2020.01.30.928051

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