Article

Fabrication of oxygen carrying microparticles functionalized with liver ECM-proteins to improve phenotypic three-dimensional in vitro liver assembly, function, and responses

2023-01-13

Abstract excerpt

Oxygen and extracellular matrix (ECM)-derived biopolymers play vital roles in regulating many cellular functions in both the healthy and diseased liver. This study reveals the importance of synergistically tuning the internal microenvironment to enhance oxygen availability alongside phenotypic ECM ligand presentation to promote native metabolic functions of human liver three-dimensional (3D) cell aggregates. First...

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Literature Corpus work: 34bcf0de-2d45-5f25-bcef-533336109a6b
DOI: 10.22541/au.167363826.67862560/v1

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