Article

A combined bioinformatics and experimental approach identifies RMI2 as a Wnt/β-catenin signaling target gene related to hepatocellular carcinoma

2022-09-12

Abstract excerpt

<h4>Background: </h4> The Wnt/β-catenin signaling pathway plays an important role in embryogenesis and tumorigenesis. In human cancer, abnormal activity of Wnt/β-catenin signaling pathway induces overexpressed of downstream genes, and initiate oncogene. There are several target genes known to be key players in tumorigenesis, such as c-myc, cyclin D1, MMPs or survivin. Therefore, identifying the target genes of Wnt...

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Literature Corpus work: 345af8d9-baac-5486-9114-7f896c783c81
DOI: 10.21203/rs.3.rs-1947817/v1

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