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Deep learning-based cell profiling based on neuronal morphology

2023-07-25

Abstract excerpt

Treatment of neurons with β-amyloid peptide (Aβ 1-42 ) has been widely used as a model to interrogate the cellular and molecular mechanisms underlying Alzheimer’s disease, and as an assay system to identify drugs that reverse or block disease phenotype. Prior studies have largely relied on high content imaging (HCI) to extract cellular features such as neurite length or branching, but these have not offered a rob...

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Literature Corpus work
3432dde1-ae2a-5f02-8356-90e0f2f7a2bb
DOI
10.1101/2023.07.23.550158
Open publication

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Deep learning-based cell profiling based on neuronal morphologyDOI 10.1101/2023.07.23.550158
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