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Article

Association Between Major Depressive Disorder and the Development of Cerebral Small Vessel Disease: A Mendelian Randomization Study

2023-11-22

Abstract excerpt

<h4>Background</h4> Although observational studies indicate a complex, bidirectional association between major depressive disorder (MDD) and cerebral small vessel disease (CSVD), the results are frequently inconsistent. This study investigated the potential correlation of MDD with both CSVD clinical outcomes and imaging markers, utilizing a bidirectional Mendelian randomization (MR) study design. <h4>Methods</h4>...

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Literature Corpus work
33ccef81-e6fd-58d6-8bb9-413345b6ffd9
DOI
10.1101/2023.11.21.23298814
Open publication

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