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Article

Ongoing evolution of SARS-CoV-2 drives escape from mRNA vaccine-induced humoral immunity.

Cell reports. Medicine - 17 Dec 2024

Roederer Alex L, Cao Yi, St Denis Kerri, Sheehan Maegan L, Li Chia Jung, Lam Evan C, Gregory David J, Poznansky Mark C, Iafrate A John, Canaday David H, Gravenstein Stefan, Garcia-Beltran Wilfredo F, Balazs Alejandro B

Abstract excerpt

With the onset of the COVID-19 pandemic 4 years ago, viral sequencing continues to document numerous individual mutations in the viral spike protein across many variants. To determine the ability of vaccine-mediated humoral immunity to combat continued SARS-CoV-2 evolution, we construct a comprehensive panel of pseudoviruses harboring each individual mutation spanning 4 years of the pandemic to understand the...

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Share to Angiotensin-Converting Enzyme 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39657661
DOI: 10.1016/j.xcrm.2024.101850
PMCID: PMC11722104

Genes

ACE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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