Article

Compound screening in primary human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies

2024-08-13

Abstract excerpt

<h4>ABSTRACT</h4> Regeneration of the airway epithelium restores barrier function and mucociliary clearance following lung injury and infection. Basal cells are tissue-resident airway stem cells that enact regeneration, yet the mechanisms regulating their proliferation and differentiation remain incompletely understood. To identify compounds that promote primary human airway basal cell proliferation, we performed...

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Literature Corpus work: 339a45fd-b1bf-56f1-bd7d-6f5a2ee3e888
DOI: 10.1101/2024.08.13.606573

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